Melania Trump is set to be in hospital for a week after having kidney surgery.
The White House revealed the US First Lady, 48, underwent a procedure to treat a benign condition this morning.
It is the most serious medical procedure undergone by a serving First Lady since Nancy Regan had a mastectomy in 1987, CNN reported.
“The procedure was successful and there were no complications,” a White House statement said.
“Mrs Trump is at Walter Reed National Military Medical Center and will likely remain there for the duration of the week.
“The First Lady looks forward to a full recovery so she can continue her work on behalf of children everywhere.”
The White House described the procedure as an embolization, which involves deliberately blocking a blood vessel. It is used by doctors to slow down blood that is flowing through a vessel too fast or shrink abnormal tissue by reducing its blood supply.
Ex-model Melania became President Trump’s third wife when she married the property billionaire in 2005.
Trump proposed by slipping a 15-carat, emerald-cut diamond ring worth $1.5 million onto her finger at New York’s glittering Met Gala.
Melania – who has been a more reserved figure in the White House than her bullish husband – launched a campaign against cyber-bullying last week.
She told an audience in the White House rose garden: “As a mother and as first lady, it concerns me that in today’s fast-paced and ever-connected world, children can be less prepared to express or manage their emotions and often times turn to forms of destructive or addictive behaviour such as bullying, drug addiction or even suicide.”
President Trump is known for his angry outbursts on Twitter.
Melania added: “I feel strongly that as adults, we can and should be best at educating our children about the importance of a healthy and balanced life.”